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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a20976188f5052e2b4a7f2519eb7628f971509aad2049868de06cc93d9dc2ab1' 
  AND token = 'DRuRvze0TJ7+UwpBIaf3kKQN+zhAFuXMPg35Csyalrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}