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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3d6a61f16c84a57e1535792c0e4756ff92c275c6d360b418792fa3c8e7286a0' 
  AND token = 'cNqn2KWAg326tBgcN2xq+wfTiL7S3UH/lJ3otugmTPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}