SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d6034942857227b01539abea3297f79b0205157c24812b989f0153e70f9760' 
  AND token = 'f2szjv6WlrWLoHOkwko4B5vE6DKiOOT+TAXM+stv27A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}