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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd0247b0b5afe948ab186f01497300d7998bc936443a5cb6b89668305719a4b9' 
  AND token = 'mqEiJwIJ9rtiG/KXjbJwC4VsPO1F7oeDTNhVTTArfRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}