SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67f9ed388f1420c04f9a971db2e3204ea923f971f91e054d791f8ff749dd95d3' 
  AND token = 'zuTwyRQb52hGrWBp2NVc/aZ07ERfBdZ7XYe3XNqx5ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}