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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53af9699bdf2db800162c1804437ebf00fb1e9599cb20c7c7c690b7f86578b3a' 
  AND token = 'qq4Wq9D6rI+ZzcqC7b2XO6FO91r96dpaRdx3v0TDNqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}