SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15470842694cb58b46c6e48b9c580cc778ce2285686ffa7d47552ac799453022' 
  AND token = '/iKZDkyZIqO48K1eeegeVS2L9GERx90sRn/G8s63dC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}