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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46faf7540b3c83f8905cc050f4ef789f4353eac8ed073e5d5272f0044d4c13df' 
  AND token = 't2/4iii5UWlU5yhclT9Vbvs0zr2xz2hhCRIC77RJikg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}