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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '346f2d9c5d3f48a8ad92813098c9e8e2f888e435238115aba90a80dab2f48df3' 
  AND token = '1hoON9T/impWOLYqLpBWO7bKAMtvvNL5zwvVARp8hsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}