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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57a11ae295fe167a8920dcd3bce1844b7ff849e5e7f6370a3e1d927aeeb67eb1' 
  AND token = 'EhyDa0mU54umHjxcMhAyacCKwS8TpLP1GB+QH9Dyvj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}