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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf4781f62272d305559e5a4cf204751e0e3d403a41c36a1606d775d3d8cdc624' 
  AND token = 'K8NBHEe/om+JZhoLYe2rC1Z7t3AosBM/U7i+VXAQ294=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}