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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64580f25c19d24c0b223bd90a325bc9a4a767ef2a47f59c4a7f8206898294ffa' 
  AND token = '1qO5v0U2Ya8o1LW5iuNILLbdM4c00Kz4dFpJQj2ErrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}