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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51c653c43a97dbe295a3690d1adbae85aebb33f35fc510ab7b9fb17e039d447a' 
  AND token = 't0KWx59HBUyLVRhzZDV6mpaYmTDfyx6cILixI4vXf28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}