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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd967980b3fd11868c7f8bf42e5c3e967a1d4805554afe3ab1cfba5687c0fa238' 
  AND token = 'ScPwlGRdRDZGxXIPFPMeQEEnmcXwKD+fojHRtdu0NuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}