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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ec5bbd16e9d159b5e6301fe853e0e4e4f536bd5a738bb3e7019a30bdf4a19c0' 
  AND token = 'v3rCUgvA+wrWkIlaDIoCAkchDybQEDZwQBYy0tIb+tM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}