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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21690cccd16430f482fc0201f70a7512cf58a376024f68d4918d90b169f6edbc' 
  AND token = 'Gzay1qxBa4721GpO7h951CMDMT/M4DJlSrfPYIDGSOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}