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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cdfac4d289198d30d152f5e373b35d022244d4ff09d6afa539cde78e85125e1' 
  AND token = 'ZFidpghVlSfLndQaR7BI+u8jRsVMJF5okpimN5B7b0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}