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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d772b50e33e8ca4ba12b7b530265b4b38eb1bc61d8f52ccd86b2639db2f9bf' 
  AND token = 'Ws7/1Ea0AyMNHoFnuo/vOJGqgNhg3BwpzJq1q7dRBNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}