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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '027f187a25e20329a96b49cdb7d82b9b9188e84245b52623f3527134153ef1c7' 
  AND token = 'd3SP0hthMhUVFh/3ErriJ7CDb71gb3tOgubeZPQT/n8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}