SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6961df1ef6255a6b0abbc0ca9ec842c1aacb5a29fef5abcd8f170becde61883' 
  AND token = 't4ynAgcp7dI/BXw02h0BbAiw1Jj0HHIzHtxe0S0EF6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}