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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59bbe7bed15c8beec875dbe02a773744d08793911fad9afe35e5a59408989547' 
  AND token = '7KBNexLumLpG79NSQ/FAH5LOoe+hc8H3k/nfwgb7nuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}