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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21643b03a65493df45395c5e0a8b4ce69b11fa721cf5d91f028846dbd71dbb25' 
  AND token = '3I1zx1Ny632IoGh18r+epNhqS9/BjgDfbQhH+O7dqRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}