SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d492bad6d3467692aed05fc1b862a9ae2a1f5d7c5fedab032dbb2e456ca533c' 
  AND token = 'zgONEROeuu0+rBajBiUlEeL0PwUu/cCJQJB+Eerp3sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}