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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8160a713489999bc9c7cca4244bd585060ee329c8a24b38b053a0cdf8ae1d0bd' 
  AND token = 'HjN4LtMGijmY50bON2DRse3LURimLeLcaRiv2wTztSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}