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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74a21e792fb77780f989d79d0a0605644e1502fe96239fdea8a8def842516f23' 
  AND token = 'K1qfATpVDfFmLBP45Yh8BnE1EZ3J2SmxrKe5qz2uI2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}