SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec2048ffc14791f45c263e646299c2af8813671f6b3c8ac7d4ad5c7c13cf7968' 
  AND token = 'f+GLDsUBt1ondBbvuFFcd/51ozlx9AIUCt+/VaUqoLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}