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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4c67a79ef48a09671ec485b6c26b7f07857d84642cae9281ef25788a19e01ff' 
  AND token = 'Ts1/juV2sK1+0NytSH+N6TRwnwIAAUYC1qDf+rBOjs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}