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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44fd6f4e505a82d7430f0d41772d556785df4c4e46a944f213df8199b2614234' 
  AND token = 'nxbXVlvM2XVzNK1PskUOKe1lwjwOmGEUaoHU01/t7X0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}