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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7efe0f4285a41f1c8019e65e929e94cf99e12644d95fd0407ae320b86098e370' 
  AND token = 'cFMpQN3Zy6ozDz8JrVe3cwG8fQsAMZ/hitL9Sl6O9u4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}