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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fe0e15c6abc7665046f057d0511a2410b7a0aad64e5aa4316c654e233e3b60b' 
  AND token = '3AeoVTJBJZ6HvUSLxye6I2ntYBNChit+KjxYSpOszNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}