SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59538ebfdd06fbdf1f093faa2368ee4175af771c61c5449fc3fa29d8413c858b' 
  AND token = 'OsVOL8WzNMy80yxYkn9jqBSu0TDqeG1k00oaeFtiytc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}