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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e9a8bfe3f7400a0b0e012cb8bad741724a4d4f87aa0bffb8b4227d566a51a24' 
  AND token = '4gTvFGli3v5tLcg+qMbcHwvrpQbPkC1s/G/Ajj0uc64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}