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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a72c6193c222f66eac74caedab69d9d1a4132b7ce1a4277861cb3ea1ec8bf41a' 
  AND token = 'wxII57mb16+PHEm/G5MPbzBx6Kd5uO2vt/cIVN3HXzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}