SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad49c099d2700b836a43bfc1c4acd6dfebbd7be7eb5d9d8f29e81b71138b336e' 
  AND token = '0AGqDYwJ6eRxBNVFCdrRWWlp/K8vvxIFEL0G7S4AgDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}