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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '438cd216b8947d4c3595c73fdcee199ee1f2367f53a9b3687566184389de70ba' 
  AND token = 'NoqePHe0QERe1T67zU8BpqoCAtuj9SPcGzB5+1Jqypw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}