SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad7564a66e01fee293ff8da30b358084b8c25286576f449b100d746ce22a5151' 
  AND token = 'EXKB6e3INjLK5GIZkffebgfY0ZQez4MdLr8CrsbErFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}