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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '327413df30ce1b9d79223a50b4b850bda6287cf7e8c8232fbb44dd8d91095ab0' 
  AND token = '6pzXp0q7iD2LuUpRck69eqP1QF2RYWvFqSAnTCXhWF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}