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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1a3a7378141738a4bebc7a4c9d2aa1457145e212422cadae07ea176cc0b9d6d' 
  AND token = '3kMiR7VPgiE60E8/3G9EzHcTgyXnHFtOrkPiodVF32s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}