SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29f16fbab05daf0644d06a3d0fae72b0e92b2cb4808a2593ea385142394c4b15' 
  AND token = 'MKeyD5pJWnyfpE7ttk4xJEsT/TNwydBLcCMi2KGAqws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00105

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}