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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bad39c144cf1f8f9798c11fd7743657e4549a6aadd6f7d7c13db50b498ba614' 
  AND token = 'S4/e9gpwGJgNhpKvEoDrsQOnTAcplpsYPQDeR1A3yoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}