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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac882155fc874d853724e85fc32413d37ca7eb3b8ea171b4aa6d9151f0d9c09' 
  AND token = 'Uf4ogu1Pu600S6ctRbpszn+LwsyLztZfmpEM9a5h5YY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}