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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f8b979d88d3d2a6dffc6884fd0a239a4d36fca75eeadd653739e49dc4b713f' 
  AND token = '2OGFFCAzS0TTOqIC+/v83OTdo1S4WVh3iKcjd8KMhEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}