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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c48635995d79b09d22e75d71fbb15f67a6a7936e24b818c4bd5bf176c8f38a9' 
  AND token = 'm9Pkj7tdp1VvfJEiMvpG1JSxqTj7AsbMr1m4TLhpeEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}