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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '148887410d54a909acf15e666fb152c3312382306a3352ed33f36261434f28a2' 
  AND token = 'fyGrDPs+o6NZTcqMC3X4n9EuCXmK0o2McCXZtWv3LgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}