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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c543fa1f6a347a1eaea539d8825a4acf8143046eabbb096ad9e3bc1aa5087278' 
  AND token = 'w8+bj8yvrgHYRN8Dcb7Rcu1fVsFX54wjC6/9I6SXjSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}