SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d27bd3c0bed5e0841bd240794a68b0a52d4c7f0df1589b3542012f4987a4807' 
  AND token = 'cBDqRtB7R4iVxAOEO7DZNTOtioNbkE3mw8LbB2Arm40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}