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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f73e3481742ae8c6041a587744a70dcc6b68bea8287e057010104d16057b74ed' 
  AND token = 'esnYswT56pPb1HHumhFE5FTrFkYA96HANEJ08QpYqtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}