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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1389ab3c4c1fe4fdf402578fe192fbe4bea94a649d1a9c8e90f8b5272f125a1a' 
  AND token = 'eC7vx3AwUJ3VC8J+iFLKlwAsY0V6Nr+opEOsELvfEH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}