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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cd36f7f7a26b5b473c6bd2126b98c20d187592437f9306ab75c4cfc418e7a74' 
  AND token = 't1jgNM/vwo5sa1miDmhD5dUrqXUmmWTesrfiMMuNOpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}