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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9aa80cfbaf7dfa080e89a8424aaf73e71da3e2982e494ff3cf8542228c598703' 
  AND token = 'G5Z40T6rFjBpBXLU566i1r43eikyUoPOqDC6KiqdoxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}